Isolation of phomopsolide A as the antimycobacterial constituent of an unidentified endophyte of the Canadian medicinal plant Geum macrophyllum

نویسندگان

  • Trina Mullin
  • Trevor N. Clark
  • John A. Johnson
چکیده

An extract of an unidentified green filamentous fungus isolated as an endophyte of the Canadian medicinal plant Geum macrophyllum exhibited significant antimycobacterial activity and a distinct 1H NMR profile. Bioassay guided fractionation indicated that the natural product phomopsolide A (1) was responsible for the distinguishing characteristics of the extract.

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تاریخ انتشار 2017